Drugs / PH-797804
last change Jun 2014 re-read 2 minutes ago

PH-797804

Small molecule targets MAPK14 via inhibition

Developed for
chronic obstructive pulmonary disease · rheumatoid arthritis · osteoarthritis · postherpetic neuralgia
Investigated by
Pfizer

Trials 16 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 19 trials
Phase 1 NCT01924650 Mar → Jun 2014 Pfizer Withdrawn No outcome recorded
Phase 1 NCT01862887 Apr → Aug 2013 Pfizer Completed No outcome recorded
Phase 1 NCT01589614 Jun → Aug 2012 Pfizer Completed No outcome recorded
Phase 1 NCT01479647 Dec 2011 → Feb 2012 Pfizer Completed No outcome recorded
Phase 1 NCT01314885 Jan → Dec 2011 chronic obstructive pulmonary disease Pfizer Completed No outcome recorded
Phase 1 NCT01226693 Nov 2010 → Mar 2011 Pfizer Completed No outcome recorded
Phase 1 NCT01217918 Oct 2010 → Feb 2011 Pfizer Completed No outcome recorded
Phase 1 NCT00827515 Feb → Apr 2009 Pfizer Withdrawn No outcome recorded
Phase 1 NCT02084485 Sep 2006 → Mar 2008 Pfizer Completed No outcome recorded
Phase 27 trials
Phase 2 NCT01543919 Apr 2012 → Sep 2013 chronic obstructive pulmonary disease Pfizer Completed No outcome recorded
Phase 2 NCT01321463 May 2011 → Jun 2012 chronic obstructive pulmonary disease Pfizer Completed No outcome recorded
Phase 2 NCT01102660 May 2010 → Feb 2011 osteoarthritis Pfizer Completed No outcome recorded
Phase 2 NCT00614705 Apr → Nov 2008 postherpetic neuralgia Pfizer Completed No outcome recorded
Phase 2 NCT00620685 Mar → Oct 2008 rheumatoid arthritis Pfizer Completed No outcome recorded
Phase 2 NCT00559910 Feb 2008 → Dec 2009 chronic obstructive pulmonary disease Pfizer Completed No outcome recorded
Phase 2 NCT00383188 Dec 2006 → Jul 2008 rheumatoid arthritis Pfizer Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 17 sources stand behind the page.

FieldValueCited text
Known as PH797804 “Study A6631027 will evaluate the safety, tolerability and pharmacokinetics of PH-797804 when administered to healthy Japanese subjects once a day (QD) for 10 days.” NCT01217918
15

NCT00827515

NCT00383188

NCT01314885

NCT00614705

NCT01102660

NCT01589614

NCT02084485

NCT01862887

NCT01543919

NCT01924650

NCT01226693

NCT01479647

NCT01321463

NCT00620685

NCT00559910

Action Inhibit “MAP kinase p38 alpha inhibitor” CHEMBL1088751
1

“A p38 inhibitor” NCT00383188

Modality Small molecule CHEMBL1088751
Route Oral “administered orally once daily” NCT00383188
Target MAPK14 “MAP kinase p38 alpha inhibitor” CHEMBL1088751