drugset / Trial / NCT02092597
Safety Evaluation of Adverse Reactions in Diabetes
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the effects of incretin-based antidiabetic therapies (DPP-4 inhibitors and GLP-1 agonists) on cardiovascular, gastrointestinal and renal system and to detail the mechanisms underlying their action in these systems.
Timeline
- Start
- 2013-10
- Primary completion
- 2015-10
- Completion
- 2016-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Exenatide | Peptide | 10 ug | Subcutaneous |
| Comparator | Gliclazide | Small molecule | 30 mg | — |
| Comparator | Linagliptin | Small molecule | 5 mg | — |