The Treatment of Glabellar Frown Lines

NCT02096081 ↗

Phase 4 Completed 250 enrolled Merz North America, Inc.

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to show that two FDA-approved botulinum toxin drugs called Xeomin® and Botox® can reduce the severity of vertical lines (wrinkles) that appear between the eyebrows (glabellar frown lines).

Timeline

Start: 2014-02
Primary completion: 2014-08
Completion: 2014-11

Publications

Results Kane MA, Gold MH, Coleman WP 3rd, Jones DH, Tanghetti EA, Alster TS, Rohrer TE, Burgess CM, Shamban AT, Finn E. A Randomized, Double-Blind Trial to Investigate the Equivalence of IncobotulinumtoxinA and OnabotulinumtoxinA for Glabellar Frown Lines. Dermatol Surg. 2015 Nov;41(11):1310-9. doi: 10.1097/DSS.0000000000000531.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Botulinum toxin type A	Protein / enzyme biologic	20 iu	Intramuscular

Indications

No indication recorded.