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drugset / Trial / NCT02102100

The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users

NCT02102100 ↗

Completed 57 enrolled Yale University National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupDouble-blindOther

Summary

This study will help determine if menthol administered by inhalation via electronic cigarettes (e-cigarette) changes the reinforcing effects of pure nicotine administered intravenously in cigarette smokers who smoke mentholated or non-mentholated cigarettes.

Timeline

Start
2014-03-26
Primary completion
2016-07-11
Completion
2016-07-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Menthol Small molecule 0 % Inhaled
Subject Menthol Small molecule 0.5 % Inhaled
Subject Menthol Small molecule 3.2 % Inhaled
Subject Nicotine Unknown 0.25 mg Intravenous
Subject Nicotine Unknown 0.5 mg Intravenous

Indications

nicotine dependence