drugset / Trial / NCT02102139
Preop Dexmedetomidine Attenuates Haemodynamic Responses to Hydrodissection
RandomizedSingle-groupTriple-blindSupportive care
Summary
Percutaneous tunnelling (hydrodissection) in the neck and anterior chest in patients undergoing robotic thyroidectomy leads to significant haemodynamic responses such as increases in blood pressure and heart rate. The investigators evaluated whether a single preoperative dexmedetomidine injection attenuated the haemodynamic responses to hydrodissection by reducing the half-maximal effective concentration (EC50) of remifentanil needed to maintain haemodynamic stability during hydrodissection.
Timeline
- Start
- 2012-05
- Primary completion
- 2012-09
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 1 ug/kg | Intravenous |
| Background | Propofol | Small molecule | — | — |
Indications
No indication recorded.