drugset / Trial / NCT02106650
Phase II Study of Folotyn With Leucovorin to Prevent/Reduce Mucositis in Patients With Hematological Malignancies
NaSingle-groupOpen-labelPrevention
Summary
This study is to evaluate the effect of leucovorin in preventing or reducing Folotyn-related Grade 2 or higher oral mucositis.
Timeline
- Start
- 2014-07
- Primary completion
- 2018-10
- Completion
- 2019-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Leucovorin | Small molecule | 25 mg | Oral |
| Background | Pralatrexate | Other / unclassified | 30 mg/m2 | Intravenous |
| Background | Vitamin B12 | Other / unclassified | 1 mg | Intramuscular |
| Background | folic acid | Other / unclassified | 1 mg | Oral |