Comparative Analysis of Cost-effectiveness of Silver Dressing in Burns

Phase 4 Completed 100 enrolled University of Sorocaba

RandomizedParallel-groupTriple-blindTreatment

Summary

The evidence is insufficient to determine whether the types of dressings containing silver differ in time / proportion for complete wound healing and pain. We will analyze the cost-effectiveness of these dressings in outpatients, considering the service provided by the Brazilian National Public Health System.

Timeline

Start: 2013-11
Primary completion: 2014-08
Completion: 2014-10

Outcome

Missed primary endpoint

paper the proportion of patients who reached the primary outcome did not differ significantly PMID 34688520 ↗

paper risk difference of -4.0 percentage points (95% confidence interval [CI], -17 to 9; P = 0.56). PMID 34688520 ↗

Publications

Moreira SS, Camargo MC, Caetano R, Alves MR, Itria A, Pereira TV, Lopes LC. Efficacy and costs of nanocrystalline silver dressings versus 1% silver sulfadiazine dressings to treat burns in adults in the outpatient setting: A randomized clinical trial. Burns. 2022 May;48(3):568-576. doi: 10.1016/j.burns.2021.05.014. Epub 2021 Jun 1.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Nanocrystalline silver	Unknown	1.64 unknown	—
Comparator	Silver Sulfadiazine	Small molecule	1 %	—

Indications

No indication recorded.