A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects

Phase 1 Completed 24 enrolled Astellas Pharma Global Development, Inc. Janssen Biotech, Inc. · collab

NaSingle-groupOpen-labelBasic science

Summary

The purpose of this study is to evaluate the effect of verapamil, a P-glycoprotein (P-gp) inhibitor, on the pharmacokinetics of ASP015K. This study will also assess the safety and tolerability of ASP015K administered alone and also and in combination with verapamil.

Timeline

Start: 2013-10
Primary completion: 2013-11
Completion: 2013-11

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Verapamil	Other / unclassified	—	Oral
Subject	peficitinib	Small molecule	—	Oral

Indications

No indication recorded.