PAIN - Postoperative Analgesia INvestigation

Phase 4 Completed 350 enrolled The University of Texas Health Science Center, Houston

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to assess the efficacy of the intraoperative injection of prolonged acting (liposomal) bupivacaine in postoperative pain control after truncal surgical incisions.

Timeline

Start: 2013-11-20
Primary completion: 2017-05-03
Completion: 2017-06-30

Publications

Sandhu HK, Miller CC 3rd, Tanaka A, Estrera AL, Charlton-Ouw KM. Effectiveness of Standard Local Anesthetic Bupivacaine and Liposomal Bupivacaine for Postoperative Pain Control in Patients Undergoing Truncal Incisions: A Randomized Clinical Trial. JAMA Netw Open. 2021 Mar 1;4(3):e210753. doi: 10.1001/jamanetworkopen.2021.0753.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	125 mg	Other
Subject	Bupivacaine	Other / unclassified	266 mg	Other
Background	Hydromorphone	Other / unclassified	0.2 mg	—
Background	Hydromorphone	Other / unclassified	0.4 mg	—
Background	Hydromorphone	Other / unclassified	2 mg	—

Indications

No indication recorded.