drugset / Trial / NCT02114775

Growth Hormone or Sildenafil as Therapies for Fatigue in Mild- Traumatic-brain-injury (MTBI)

NCT02114775

RandomizedCrossoverQuadruple-blindDiagnostic

Summary

The overall goal is to determine whether perceptual or performance fatigue can be reduced in MTBI patients with and without growth hormone (GH) deficiency by treating them in a crossover fashion based upon GH status. A battery of functional, fatigue, cognitive, imaging and blood flow tests will be performed to assess the efficacy of the two drug interventions, Growth hormone and Sildenafil.

Timeline

Start
2014-12-12
Primary completion
2017-11-10
Completion
2017-11-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Sildenafil Unknown 50 mg Oral
Comparator Somatropin Protein / enzyme biologic 0.6 mg Subcutaneous