drugset / Trial / NCT02114775
Growth Hormone or Sildenafil as Therapies for Fatigue in Mild- Traumatic-brain-injury (MTBI)
RandomizedCrossoverQuadruple-blindDiagnostic
Summary
The overall goal is to determine whether perceptual or performance fatigue can be reduced in MTBI patients with and without growth hormone (GH) deficiency by treating them in a crossover fashion based upon GH status. A battery of functional, fatigue, cognitive, imaging and blood flow tests will be performed to assess the efficacy of the two drug interventions, Growth hormone and Sildenafil.
Timeline
- Start
- 2014-12-12
- Primary completion
- 2017-11-10
- Completion
- 2017-11-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sildenafil | Unknown | 50 mg | Oral |
| Comparator | Somatropin | Protein / enzyme biologic | 0.6 mg | Subcutaneous |