Efficacy and Mortality of a Loading Dose of Colistin in Critical Ill Patients

Summary

The study hypothesis is that the loading dose of intravenous colistin (6 million of international units) is associated with greater clinical and microbiological efficacy, and reduced mortality of critically ill patients infected by multidrug resistant Gram- negative bacilli, compared to a scheme without loading dose.

Timeline

Start

2014-04

Primary completion

2018-12

Completion

2018-12

Drugs

Indications