drugset / Trial / NCT02123381
Changes in Tumor Tissue and Serum Biomarkers Before and After Cetuximab Combined With Preoperative Radiotherapy in Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
Phase 2
Unknown
100 enrolled
Sichuan Cancer Hospital and Research Institute
Affiliated Cancer Hospital & Institute of Guangzhou Medical University · collabDaping Hospital and the Research Institute of Surgery of the Third Military Medical University · collabSouthwest Hospital, China · collabXinqiao Hospital of Chongqing · collab
NaSingle-groupOpen-labelTreatment
Summary
This study aim to investigate Changes in tumor tissue and serum biomarkers before and after cetuximab combined with preoperative radiotherapy in locally advanced thoracic middle-lower segment esophageal squamous cell carcinoma.We want to find one or more effective biomarkers to predict and evaluate the patients who will be benefit from cetuximab combined with preoperative radiotherapy.
Timeline
- Start
- 2014-04
- Primary completion
- 2020-07
- Completion
- 2020-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cetuximab | Monoclonal antibody | 250 mg/m2 | Intravenous |