Rediscovering Hydroxychloroquine as a Novel Insulin Sensitizer

Summary

Current options to treat insulin resistance in diabetes are fairly limited. For this reason, novel treatments would represent a major progress. The generic drug hydroxychloroquine (HCQ) has poorly understood effects on blood sugar metabolism. In this study, the investigators will examine the mechanisms by which this drug affects glucose metabolism and which cells are affected. Findings emanating from this project will help establish whether HCQ may be a viable treatment for disorders of glucose metabolism.

Timeline

Start

2014-04

Primary completion

2016-08

Completion

2016-08

Drugs

Indications

No indication recorded.