drugset / Trial / NCT02124941

Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS

NCT02124941

RandomizedSingle-groupOpen-labelDiagnostic

Summary

This study is designed to look at the relationship between brain glucose utilization, neurotransmission (e.g., glutamate, also known as the main excitatory amino-acid neurotransmitter in the brain), and synaptic density. This relationship will be explored in the brain's prefrontal cortex, an area important in decision-making and impulsivity.

Timeline

Start
2014-02
Primary completion
2022-08-14
Completion
2022-08-14

Drugs

EvaluationDrugModalityDoseRoute
Comparator N-acetylcysteine Small molecule 3600 mg

Indications