drugset / Trial / NCT02124941
Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS
RandomizedSingle-groupOpen-labelDiagnostic
Summary
This study is designed to look at the relationship between brain glucose utilization, neurotransmission (e.g., glutamate, also known as the main excitatory amino-acid neurotransmitter in the brain), and synaptic density. This relationship will be explored in the brain's prefrontal cortex, an area important in decision-making and impulsivity.
Timeline
- Start
- 2014-02
- Primary completion
- 2022-08-14
- Completion
- 2022-08-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | N-acetylcysteine | Small molecule | 3600 mg | — |