drugset / Trial / NCT02133612

Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Thoracic Esophageal Squamous Cell Carcinoma

NCT02133612 ↗

Phase 2 Completed 43 enrolled Chinese Academy of Medical Sciences
NaSingle-groupOpen-labelTreatment

Summary

Esophageal cancer is a highly aggressive malignancy with a poor overall outcome. * Five year survival rate after radical esophagectomy is modest at about 40%.The patients with regional lymph node metastases have worse outcome than those without lymph node metastases. * No standard postoperative adjuvant chemotherapy has ever been established.

Timeline

Start
2007-12
Primary completion
2012-05
Completion
2014-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 50 mg/m2 Intravenous
Subject Paclitaxel Small molecule 150 mg/m2 Intravenous

Indications