drugset / Trial / NCT02137395
The Effect of Dexamethasone on Sugammadex Reversal
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine whether dexamethasone extends the duration of recovery from anesthesia.
Timeline
- Start
- 2014-06
- Primary completion
- 2015-05
- Completion
- 2015-05
Publications
- Results Rezonja K, Sostaric M, Vidmar G, Mars T. Dexamethasone produces dose-dependent inhibition of sugammadex reversal in in vitro innervated primary human muscle cells. Anesth Analg. 2014 Apr;118(4):755-63. doi: 10.1213/ANE.0000000000000108.
- Results Plaud B, Meretoja O, Hofmockel R, Raft J, Stoddart PA, van Kuijk JH, Hermens Y, Mirakhur RK. Reversal of rocuronium-induced neuromuscular blockade with sugammadex in pediatric and adult surgical patients. Anesthesiology. 2009 Feb;110(2):284-94. doi: 10.1097/ALN.0b013e318194caaa.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 0.5 mg/kg | Intravenous |
Indications
No indication recorded.