drugset / Trial / NCT02141620
n-Acetylcysteine and Cocaine
Phase 0
Completed
15 enrolled
University of Kentucky
National Institute on Drug Abuse (NIDA) · collab
RandomizedCrossoverTriple-blindBasic science
Summary
This study will determine the initial efficacy, safety and tolerability of n-acetylcysteine as a pharmacotherapy for cocaine dependence. A rigorous, inpatient human laboratory study will be conducted in which the subjective, physiological and reinforcing effects of cocaine are evaluated during maintenance on placebo and n-acetylcysteine.
Timeline
- Start
- 2014-05
- Primary completion
- 2016-04
- Completion
- 2016-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cocaine | Small molecule | — | — |
| Subject | N-acetylcysteine | Small molecule | — | Oral |