drugset / Trial / NCT02146833

SHIP (Selinexor in Hormone Insensitive Prostate Cancer)

NCT02146833 ↗

Phase 2 Terminated 20 enrolled Karyopharm Therapeutics Inc
RandomizedSingle-groupOpen-labelTreatment

Summary

This is an open-label, Phase 2 clinical study of the oral Selective Inhibitor of Nuclear Export (SINE) selinexor (KPT-330) in patients with metastatic castration-resistant prostate cancer (mCRPC).

Timeline

Start
2014-05
Primary completion
2016-04-01
Completion
2016-04-01

Outcome

Outcome not reported

Stopped (Enrollment): “Due to enrollment challenges. The termination is not a consequence of any safety concern.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Selinexor Other / unclassified 60 mg Oral
Subject Selinexor Other / unclassified 80 mg Oral

Indications