Drugs / Selinexor
last change 3 days ago re-read 2 minutes ago

Selinexor

also known as KPT-330 · ATG-010 · SEL · Xpovio · KCP-330 · Nexpovio

Other / unclassified targets XPO1 via inhibition

Developed for
plasma cell myeloma · acute myeloid leukemia · diffuse large B-cell lymphoma · refractory plasma cell neoplasm · myelodysplastic syndrome · myelofibrosis · peripheral T-cell lymphoma, not otherwise specified · endometrial cancer
+111 more · lymphoma · cancer · mature T-cell and NK-cell non-Hodgkin lymphoma · small cell lung carcinoma · soft tissue sarcoma · B-cell non-Hodgkin lymphoma · COVID-19 · extranodal nasal NK/T cell lymphoma · glioblastoma · malignant peripheral nerve sheath tumor · mantle cell lymphoma · metastatic malignant neoplasm · ovarian cancer · primary central nervous system lymphoma · alveolar soft part sarcoma · liposarcoma · mixed phenotype acute leukemia · non-small cell lung carcinoma · ovarian carcinoma · pancreatic ductal adenocarcinoma · sarcoma · T-cell and NK-cell neoplasm · thymoma · triple-negative breast carcinoma · acute leukemia of ambiguous lineage · acute lymphoblastic leukemia · acute myeloid leukemia by FAB classification · acute myeloid leukemia with 11q23 abnormalities · acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) · acute myeloid leukemia with t(8;21)(q22;q22) translocation · acute promyelocytic leukemia · AL amyloidosis · amyloidosis · angiosarcoma · atypical teratoid rhabdoid tumor · B-cell neoplasm · blast phase chronic myelogenous leukemia, BCR-ABL1 positive · breast cancer · central nervous system cancer · central nervous system non-hodgkin lymphoma · cervical carcinoma · childhood acute lymphoblastic leukemia · childhood acute myeloid leukemia · chronic lymphocytic leukemia/small lymphocytic lymphoma · chronic myelomonocytic leukemia · colorectal cancer · colorectal neoplasm · cutaneous melanoma · dedifferentiated liposarcoma · diffuse large B-cell lymphoma germinal center B-cell type · endometrial carcinoma · endometrial stromal tumor · Epstein-Barr virus infection · esophageal cancer · Ewing sarcoma · extraosseous osteosarcoma · fallopian tube carcinoma · fibrosarcoma · follicular lymphoma · gastric cancer · gastrointestinal stromal tumor · gliosarcoma · grade III glioma · hematopoietic and lymphoid cell neoplasm · hepatocellular carcinoma · high grade malignant neoplasm · high-grade B-cell lymphoma double-hit/triple-hit · histiocytic and dendritic cell neoplasm · histiocytoma, Angiomatoid fibrous · Hodgkins lymphoma · hormone-resistant prostate carcinoma · IDH-wildtype glioblastoma · indolent B-cell non-Hodgkin lymphoma · Langerhans cell histiocytosis · leiomyosarcoma · malignant glioma · MALT lymphoma · melanoma · metastatic malignant neoplasm in the brain · metastatic melanoma · metastatic prostate carcinoma · myeloid neoplasm · myeloproliferative neoplasm · myoepithelial tumor · myxofibrosarcoma · neural glioblastoma · neuroendocrine carcinoma · non-Hodgkin lymphoma · pancreatic acinar cell carcinoma · primary brain neoplasm · primary cutaneous T-cell lymphoma · primary myelofibrosis · primary peritoneal carcinoma · prolymphocytic leukemia · prostate adenocarcinoma · prostate cancer · rectal neoplasm · refractory malignant neoplasm · relapsed/refractory diffuse large B-cell lymphoma · renal cell adenocarcinoma · rhabdoid tumor · Richter transformation · salivary gland cancer · smoldering plasma cell myeloma · squamous cell carcinoma · squamous cell lung carcinoma · thrombocytopenia · ulcer of lower limbs · urothelial carcinoma · Waldenstrom macroglobulinemia · Wilms tumor
Investigated by
Karyopharm Therapeutics Inc · National Cancer Institute (NCI) · Antengene Corporation · Ruijin Hospital · H. Lee Moffitt Cancer Center and Research Institute · St. Jude Children's Research Hospital
+148 more · The First Affiliated Hospital of Soochow University · AbbVie · Memorial Sloan Kettering Cancer Center · Sun Yat-sen University · University Health Network, Toronto · Beijing Tongren Hospital · Fudan University · GSO Global Clinical Research BV · Hackensack Meridian Health · Institute of Hematology & Blood Diseases Hospital, China · M.D. Anderson Cancer Center · National University Hospital, Singapore · Tianjin Medical University Cancer Institute and Hospital · University of Chicago · Washington University School of Medicine · Weill Medical College of Cornell University · Belgian Gynaecological Oncology Group · Erin Bertino · GOG Foundation · Israeli Society of Gynecologic Oncology · Janssen, LP · Mayo Clinic · Multicenter Italian Trials in Ovarian Cancer (MITO) · North Eastern German Society of Gynaecological Oncology · Oncotherapeutics · PETHEMA Foundation · Peking University People's Hospital · Shanghai Tong Ren Hospital · Spanish Group for Research in Sarcomas · Spanish Ovarian Cancer Research Group · Takeda · The Central and Eastern European Gynecologic Oncology Group · The First Hospital of Jilin University · West China Hospital · Academic and Community Cancer Research United · Affiliated Hospital of Jiangnan University · Alice Mims · Anhui Provincial Cancer Hospital · Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas · Australia New Zealand Gynaecological Oncology Group · Barbara Ann Karmanos Cancer Institute · Beijing Friendship Hospital · Bhavana Bhatnagar · Bing Han · Bristol-Myers Squibb · Caligor Coghlan (CalCog) · Canadian Cancer Trials Group · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Cancer Trials Ireland (CTI) · Celgene Corporation · Children's Oncology Group · Chinese PLA General Hospital · Chongqing University Cancer Hospital · Chunrui Li · Chunyan Sun, MD · College of Pharmaceutical Sciences at Zhejiang University · Columbia University · Daihong Liu · Dana-Farber Cancer Institute · Donghua Zhang · Duke University · Eli Lilly and Company · European Myeloma Network B.V. · European Network of Gynaecological Oncological Trial Groups (ENGOT) · FDA Office of Orphan Products Development · Gabrail Cancer Center Research · Gateway for Cancer Research · Genentech, Inc. · Georgetown University · GlaxoSmithKline · Gustave Roussy, Cancer Campus, Grand Paris · Hellenic Cooperative Oncology Group · Hospices Civils de Lyon · Ida Bruun Kristensen · all 154 on the full record

Regulatory milestones approvals, filings & regulatory actions · 5 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (3) US (FDA) XPOVIO 2020-06-22 – 2026-04-23 fda.gov
Approved EU (EMA) Nexpovio 2021-03-26 europa.eu
Approved US (FDA) XPOVIO 2019-07-03 fda.gov

Trials 190 · started per year

today
US approved 2019
EU approved 2021
2
1
24
22
5
5
7
5
13
22
17
20
17
17
11
2013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT04984330 Dec 2021 → Jun 2023 AL amyloidosis Weill Medical College of Cornell University Withdrawn No outcome recorded
Phase 142 trials
Phase 1 NCT07200102 Mar 2026 → Apr 2029 expected plasma cell myeloma Washington University School of Medicine Recruiting No outcome recorded
Phase 1 NCT07094464 Jun 2025 → Jun 2027 expected acute myeloid leukemia, disease related to hematopoietic stem cell transplant Daihong Liu Active not recruiting No outcome recorded
Phase 1 NCT06225310 Aug 2024 → Apr 2027 expected plasma cell myeloma Oncotherapeutics Recruiting No outcome recorded
Phase 1 NCT05952687 Mar 2024 → Sep 2025 atypical teratoid rhabdoid tumor St. Jude Children's Research Hospital Withdrawn No outcome recorded
Phase 1 NCT05354362 Mar 2022 → Feb 2023 relapsed/refractory diffuse large B-cell lymphoma Antengene Corporation Terminated No outcome recorded
Phase 1 NCT05201118 Jan → Dec 2022 plasma cell myeloma Chunrui Li Unknown No outcome recorded
Phase 1 NCT04898894 Nov 2021 → Jul 2023 overdue acute leukemia of ambiguous lineage St. Jude Children's Research Hospital Active not recruiting No outcome recorded
Phase 1 NCT05093608 Nov 2021 → Oct 2022 hepatocellular carcinoma H. Lee Moffitt Cancer Center and Research Institute Terminated No outcome recorded
Phase 1 NCT04811196 Mar 2021 → May 2025 endometrial stromal tumor, leiomyosarcoma, malignant peripheral nerve sheath tumor University Health Network, Toronto Completed No outcome recorded
Phase 1 NCT04850755 Mar 2021 → Mar 2025 high grade malignant neoplasm, metastatic malignant neoplasm National University Hospital, Singapore Completed No outcome recorded
Phase 1/238 trials
Phase 1/2 NCT07706959 Jul 2026 → Jan 2028 expected peripheral T-cell lymphoma, not otherwise specified Ruijin Hospital Not yet recruiting No outcome recorded
Phase 1/2 NCT07479979 Jul 2026 → Jul 2027 expected plasma cell myeloma Natalie Callander Recruiting No outcome recorded
Phase 1/2 NCT06966154 May 2025 → May 2027 expected T-cell and NK-cell neoplasm, extranodal nasal NK/T cell lymphoma Fudan University Recruiting No outcome recorded
Phase 1/2 NCT06559553 Sep 2024 → Dec 2026 expected T-cell and NK-cell neoplasm Mingzhi Zhang Recruiting No outcome recorded
Phase 1/2 NCT06556199 Aug 2024 → Aug 2026 overdue primary central nervous system lymphoma Second Affiliated Hospital, School of Medicine, Zhejiang University Recruiting No outcome recorded
Phase 1/2 NCT06552559 May 2024 → Dec 2028 expected B-cell non-Hodgkin lymphoma, metastatic malignant neoplasm in the brain Samsung Medical Center Recruiting No outcome recorded
Phase 1/2 NCT06239272 Mar 2024 → Jun 2034 expected angiosarcoma, extraosseous osteosarcoma, fibrosarcoma, histiocytoma, Angiomatoid fibrous +3 St. Jude Children's Research Hospital Recruiting No outcome recorded
Phase 1/2 NCT05975944 Sep 2023 small cell lung carcinoma Tianjin Medical University Cancer Institute and Hospital Unknown No outcome recorded
Phase 1/2 NCT05698147 Aug 2023 → Jun 2026 overdue central nervous system cancer Tong Chen, MD Recruiting No outcome recorded
Phase 1/2 NCT06449482 May 2023 → Mar 2025 acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China Terminated No outcome recorded
Phase 283 trials
Phase 2 NCT07626021 Jul → Aug 2026 overdue myeloproliferative neoplasm Zhongshan Hospital (Xiamen), Fudan University Not yet recruiting No outcome recorded
Phase 2 NCT07554482 May 2026 → Dec 2027 expected mature T-cell and NK-cell non-Hodgkin lymphoma Beijing Tongren Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07574528 May 2026 → Mar 2028 expected extranodal nasal NK/T cell lymphoma Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 2 NCT07447817 May 2026 → May 2030 expected myelofibrosis John Mascarenhas Not yet recruiting No outcome recorded
Phase 2 NCT07523737 Apr 2026 → Mar 2028 expected diffuse large B-cell lymphoma, primary central nervous system lymphoma Beijing Tongren Hospital Recruiting No outcome recorded
Phase 2 NCT07405255 Jan 2026 → Dec 2027 expected lymphoma Ruijin Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07276698 Dec 2025 → Dec 2029 expected mature T-cell and NK-cell non-Hodgkin lymphoma Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Not yet recruiting No outcome recorded
Phase 2 NCT07172412 Nov 2025 → Dec 2027 expected small cell lung carcinoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06822972 Aug 2025 → Dec 2026 expected plasma cell myeloma Duke University Recruiting No outcome recorded
Phase 2 NCT07204041 Aug 2025 → Aug 2027 expected Langerhans cell histiocytosis Cancer Institute and Hospital, Chinese Academy of Medical Sciences Active not recruiting No outcome recorded
Phase 2/34 trials
Phase 2/3 NCT07369739 Jan 2026 → Jan 2027 expected Epstein-Barr virus infection, histiocytosis Beijing Friendship Hospital Recruiting No outcome recorded
Phase 2/3 NCT05822050 Jun 2023 → Dec 2024 The First Hospital of Jilin University Unknown No outcome recorded
Phase 2/3 NCT04442022 Sep 2020 → Dec 2026 expected diffuse large B-cell lymphoma Karyopharm Therapeutics Inc Active not recruiting No outcome recorded
Phase 2/3 NCT02606461 Jan 2016 → Oct 2020 dedifferentiated liposarcoma Karyopharm Therapeutics Inc Completed No outcome recorded
Phase 311 trials
Phase 3 NCT07138209 Nov 2025 → Dec 2027 expected refractory plasma cell neoplasm Qilu Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 3 NCT06613035 Sep 2024 → Sep 2027 expected acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China Not yet recruiting No outcome recorded
Phase 3 NCT06158841 May 2024 → Dec 2027 expected plasma cell myeloma AbbVie Recruiting No outcome recorded
Phase 3 NCT05611931 Apr 2023 → Aug 2026 overdue endometrial cancer Karyopharm Therapeutics Inc Active not recruiting No outcome recorded
Phase 3 NCT05726110 Jan 2023 → Dec 2024 overdue acute myeloid leukemia Shanxi Bethune Hospital Recruiting No outcome recorded
Phase 3 NCT05028348 Apr 2022 → Mar 2026 overdue plasma cell myeloma European Myeloma Network B.V. Active not recruiting No outcome recorded
Phase 3 NCT04939142 Jul 2021 → Dec 2025 overdue refractory plasma cell neoplasm Antengene Corporation Active not recruiting No outcome recorded
Phase 3 NCT04562389 Mar 2021 → Feb 2026 overdue myelofibrosis Karyopharm Therapeutics Inc Active not recruiting No outcome recorded
Phase 3 NCT04534725 Dec 2020 → Nov 2022 COVID-19, cancer, viral respiratory tract infection Peter MacCallum Cancer Centre, Australia Completed No outcome recorded
Phase 3 NCT03555422 Jan 2018 → Jan 2022 endometrial cancer Karyopharm Therapeutics Inc Completed No outcome recorded
Phase 42 trials
Phase 4 NCT07264894 Dec 2025 → Dec 2027 expected mantle cell lymphoma Zhengzhou University Not yet recruiting No outcome recorded
Phase 4 NCT05786989 Feb 2023 → Mar 2024 diffuse large B-cell lymphoma Chongqing University Cancer Hospital Unknown No outcome recorded
Phase not applicable7 trials
NCT07632170 Nov 2026 → Oct 2027 expected myeloid neoplasm Bing Han Not yet recruiting No outcome recorded
NCT07191431 Sep 2025 → Sep 2027 expected central nervous system non-hodgkin lymphoma Ruijin Hospital Recruiting No outcome recorded
NCT06853678 Feb 2025 → Jul 2026 overdue small cell lung carcinoma Tianjin Medical University Cancer Institute and Hospital Recruiting No outcome recorded
NCT07074470 Jan 2025 → Jan 2030 expected primary central nervous system lymphoma The First Affiliated Hospital of Soochow University Recruiting No outcome recorded
NCT07236931 Jan 2025 → May 2026 acute myeloid leukemia Donghua Zhang Completed No outcome recorded
NCT05805072 May 2023 → Jun 2024 acute myeloid leukemia The First Affiliated Hospital of Soochow University Unknown No outcome recorded
NCT02069730 Jun 2014 → Jun 2023 metastatic malignant neoplasm, salivary gland cancer University Health Network, Toronto Completed No outcome recorded
Phase not stated2 trials
NCT03850704 plasma cell myeloma Masonic Cancer Center, University of Minnesota No longer available No outcome recorded
NCT07215832 diffuse large B-cell lymphoma, endometrial cancer, myelofibrosis, neural glioblastoma +3 Karyopharm Therapeutics Inc Available No outcome recorded
Also used as a comparator or background therapy in 5 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 34 trials
Phase 3 NCT07569757 Comparator Jun 2026 → Dec 2028 expected plasma cell myeloma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Not yet recruiting No outcome recorded
Phase 3 NCT07579234 Comparator Jan 2026 → Jan 2029 expected refractory plasma cell neoplasm Shandong New Time Pharmaceutical Co., LTD Recruiting No outcome recorded
Phase 3 NCT07011056 Comparator Jul 2025 → Jun 2029 expected diffuse large B-cell lymphoma Chengdu Zenitar Biomedical Technology Co., Ltd Recruiting No outcome recorded
Phase 3 NCT05675319 Comparator Mar 2023 → Mar 2025 plasma cell myeloma University Medical Center Hamburg-Eppendorf Terminated No outcome recorded
Phase not applicable1 trial
NCT06265545 Background Feb 2024 → Jan 2026 overdue acute myeloid leukemia, refractory hematologic cancer Institute of Hematology & Blood Diseases Hospital, China Recruiting No outcome recorded

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 200 sources stand behind the page.

FieldValueCited text
Known as Selinexor “This study aims to evaluate the efficacy and safety of the VPX regimen, a novel combination of teniposide, PD-1 monoclonal antibody and selinexor, in patients with...” NCT07074470
184

“For relapsed refractory MCL patients who had received BTK inhibitors: selinexor 60mg once daily on days 1 and 8, zuberitamab 375 mg/m² on day 0, Dexamethasone 20 mg on days 1-3...” NCT07264894

Selinexor plus tislelizumab in patients with relapsed/refractory natural killer/T-cell lymphoma after failure of PD-1 blockade: the phase 1b TOUCH trial.” PMID 42438166 Aug 2026

“the XAB regimen: a chemotherapy-free or low-dose chemotherapy regimen containing selinexor (X), azacitidine (A), and venetoclax (B)” NCT07236931

Selinexor: 60 mg on days 1, 8, and 15, q3w, for a total of 6 cycles” NCT07523737

“COPL + XPO1 inhibitor (Selinexor, 60 mg, po., d1,8,15)” NCT05833893

Selinexor 40mg/d,po d1,8,15” NCT06062641

NCT07437170

NCT02178436

NCT07574528

NCT07276698

NCT05498636

NCT02137356

NCT04764942

NCT05675319

NCT02120222

NCT04595994

NCT07172412

NCT06966154

NCT04562389

NCT02536495

NCT06158841

NCT02228525

NCT05675813

NCT02389543

NCT04984330

NCT04925193

NCT02831686

NCT03071276

NCT04355676

NCT02835222

NCT04898894

NCT02249091

NCT04640779

NCT02213133

NCT04939142

NCT06556199

NCT03850704

NCT02628704

NCT02530476

NCT02283359

NCT07479979

NCT04850755

NCT07138209

NCT02250885

NCT02093403

NCT02384850

NCT07369739

NCT03042819

NCT05736965

NCT02343042

NCT05432804

NCT05028348

NCT07447817

NCT06225310

NCT02416908

NCT06664970

NCT04768881

NCT04854434

NCT04216329

NCT02146833

NCT06765928

NCT05333458

NCT05736978

NCT02741388

NCT06449482

NCT01986348

NCT07011056

NCT04421378

NCT04607772

NCT02606461

NCT05983276

NCT02199665

NCT05035745

NCT02215161

NCT06559553

NCT04534725

NCT03732703

NCT06169215

NCT06900088

NCT04717700

NCT05900882

NCT06652139

NCT02269293

NCT07405255

NCT03110562

NCT04877275

NCT03661515

NCT02780609

NCT06265545

NCT02336815

NCT07554482

NCT05980806

NCT05201118

NCT06239272

NCT04442022

NCT04138381

NCT02323880

NCT02419495

NCT07706959

NCT05093608

NCT05726110

NCT03589222

NCT02303392

NCT04811196

NCT02088541

NCT02314247

NCT07626021

NCT05177276

NCT05805072

NCT03955783

NCT03555422

NCT04562870

NCT06114004

NCT05322330

NCT06517511

NCT06822972

NCT01607905

NCT05478993

NCT02573363

NCT03627403

NCT05820763

NCT02227251

NCT07215832

NCT03193437

NCT07200102

NCT02351505

NCT05822050

NCT02212561

NCT04756401

NCT05698147

NCT03880123

NCT05951855

NCT02431351

NCT03466827

NCT04891744

NCT04519476

NCT02186834

NCT07579234

NCT02485535

NCT02138786

NCT04843579

NCT02403310

NCT04856189

NCT04414475

NCT05974085

NCT05786989

NCT06744894

NCT02299518

NCT02402764

NCT05975944

NCT05530421

NCT03147885

NCT06212596

NCT05952687

NCT02367690

NCT03095612

NCT05577364

NCT07094464

NCT07191431

NCT03212937

NCT05597345

NCT05099003

NCT06552559

NCT04782687

NCT04349098

NCT07569757

NCT02436707

NCT05170789

NCT05985161

NCT05422027

NCT05422066

NCT06573151

NCT02025985

NCT06573138

NCT07002099

NCT02069730

NCT05611931

NCT07204041

NCT06813079

NCT07632170

NCT06853678

NCT04661137

NCT04941937

NCT06613035

Known as ATG-010 “ATG 010 40mg/once, will be given on Days 1, 8, and 15 of each cycle” NCT04425070
7

ATG-010 60 mg/once, oral, on Days 4 and 11.” NCT04425070

“Selinexor(ATG-010)” NCT04941937

NCT03992339

NCT05354362

NCT03944057

NCT04998760

NCT05265975

Known as KCP-330 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01896505
Known as KPT-330 “Selinexor (KPT-330, Xpovio) is a first in class selective inhibitor of nuclear export which has been approved for use in relapsed and refractory multiple myeloma (RRMM).” NCT04925193
12

“Selinexor (also called KPT-330), works by trapping "tumor suppressor proteins" within the cell and thus causing the cancer cells to die or stop growing.” NCT03042819

“This schedule will be combined with oral selinexor (KPT-330) for three weeks at days and dose according to escalation level:” NCT03661515

“Study Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Participants With Recurrent Gliomas” NCT01986348

“Selinexor (KPT-330) is a first-in-class, oral selective exportin 1 (XPO1) inhibitor (1,2).” NCT06225310

“A Phase 1 Study of Selinexor (KPT-330), A Selective XPO1 Inhibitor” NCT02323880

“Selective Inhibitor Of Nuclear Export (SINE) Selinexor (KPT-330)” NCT02249091

“Drug: selinexor (KPT-330)” NCT02228525

“Selinexor (KPT-330)” NCT02831686

NCT02091245

NCT02471911

NCT01607892

NCT02078349

Known as Nexpovio ChEMBL registry synonym — accepted as the source's own label CHEMBL3545185
Known as SEL “Preclinical studies showed a synergistic antileukemia activity with combination of selective XPO1 inhibitor selinexor (SEL) and venetoclax (VEN), with potential to overcome VEN...” PMID 41796974 Mar 2026
1

“BACKGROUND: Selinexor (SEL) is an oral inhibitor of nuclear export protein Exportin 1 (XPO1) previously shown to upregulate programmed cell death protein 1 (PD-L1) and...” PMID 40502306 Jun 2025

Known as Xpovio “Selinexor (KPT-330, Xpovio) is a first in class selective inhibitor of nuclear export which has been approved for use in relapsed and refractory multiple myeloma (RRMM).” NCT04925193
1

“Selinexor Oral Tablet [Xpovio]” NCT06517511

Action Inhibit “selective inhibitor of the nuclear export protein XPO1” PMID 29203585 Dec 2017
Modality Other / unclassified “SINE™ compound selinexor” NCT02314247
Route Oral “Participants with colorectal cancer and liver metastasis received oral selinexor as single agent” NCT01607905
Target XPO1 “selective inhibitor of the nuclear export protein XPO1PMID 29203585 Dec 2017