drugset / Trial / NCT02351505

Selinexor in Treating Patients With Relapsed Small Cell Lung Cancer

NCT02351505

Phase 2 Terminated 1 enrolled Erin Bertino Karyopharm Therapeutics Inc · collab
NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well selinexor work in treating patients with small-cell lung cancer that has returned after a period of improvement. One specific way cancer cells continue to grow is by getting rid of certain proteins called "tumor suppressor proteins: that would normally cause cancer cells to die. Selinexor works by trapping "tumor suppressing proteins" within the cell and may cause the cancer cells to die or stop growing.

Timeline

Start
2015-05
Primary completion
2015-12
Completion
2016-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Selinexor Other / unclassified Oral