drugset / Trial / NCT04877275
ATG-010(Selinexor) in Combination With Chemotherapy in RRMM
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is a single-arm that includes two experimental arms,Selinexor(ATG-010) in Combination with Chemotherapy to Treat Relapsed/Refractory Multiple Myeloma Patients.To evaluate efficacy and safety of ATG-010 in combination with chemotherapy in RRMM patients received at least one prior lines of therapy
Timeline
- Start
- 2021-05-21
- Primary completion
- 2024-12-30
- Completion
- 2024-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | 300 mg/m2 | — |
| Subject | Doxorubicin | Other / unclassified | 25 mg/m2 | Intravenous |
| Subject | Selinexor | Other / unclassified | 80 mg | Oral |
| Subject | Selinexor | Other / unclassified | 100 mg | Oral |
| Background | Dexamethasone | Small molecule | 40 mg | — |