Evaluation of the Effects of Etifoxine 100 mg and Lorazepam 2 mg on Vigilance and Cognitive Functions in the Elderly

Phase 3 Completed 31 enrolled Biocodex

RandomizedCrossoverDouble-blindBasic science

Summary

The purpose of this study is to evaluate the effects of etifoxine (an anxiolytic) compared to lorazepam (a benzodiazepine anxiolytic) on vigilance and cognitive functions in the elderly.

Timeline

Start: 2013-12
Primary completion: 2015-10
Completion: 2015-10

Publications

Deplanque D, Machuron F, Waucquier N, Jozefowicz E, Duhem S, Somers S, Colin O, Duhamel A, Bordet R. Etifoxine impairs neither alertness nor cognitive functions of the elderly: A randomized, double-blind, placebo-controlled crossover study. Eur Neuropsychopharmacol. 2018 Aug;28(8):925-932. doi: 10.1016/j.euroneuro.2018.05.011. Epub 2018 Jun 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Etifoxine	Small molecule	100 mg	Oral
Comparator	Lorazepam	Small molecule	2 mg	Oral

Indications

No indication recorded.