A Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With Moderately Diminished Liver Function Compared to Those With Normal Liver Function

Phase 1 Completed 16 enrolled Astellas Pharma Europe B.V. Kyntra Bio · collab

Non-randomizedSingle-groupOpen-labelBasic science

Summary

The effect of moderately diminished liver function on the exposure, safety and tolerability of a single dose of FG-4592 is studied in male and female subjects. The results are compared to the data gained from subjects with normal liver function.

Timeline

Start: 2013-09
Primary completion: 2013-12
Completion: 2013-12

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Roxadustat	Small molecule	—	Oral

A Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With Moderately Diminished Liver Function Compared to Those With Normal Liver Function

Summary

Timeline

Drugs

Indications