drugset / Trial / NCT02166229

Divalproex Sodium in the Treatment of the Cutaneous Manifestations of Scleroderma

NCT02166229

Phase 1/2 Withdrawn Yale University
NaSingle-groupOpen-labelTreatment

Summary

To investigate the ability of divalproex sodium, a histone deacetylase inhibitor, to improve the digital manifestations of scleroderma including digital edema, calcinosis cutis, digital ulcers, and joint contractures.

Timeline

Start
2014-06
Primary completion
2014-08
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Divalproex Sodium Small molecule 500 mg

Indications