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drugset / Trial / NCT02169895

Pharmacokinetic-pharmacodynamic Interaction Between Three Different Single Doses of BIA 9-1067 and a Single-dose of Immediate-release Levodopa/Benserazide

NCT02169895 ↗

Phase 1 Completed 16 enrolled Bial - Portela C S.A.
RandomizedCrossoverDouble-blindTreatment

Summary

To investigate the effect of three single oral doses of BIA 9-1067 (25 mg, 50 mg and 100 mg) on the levodopa pharmacokinetics when administered in combination with a single-dose of immediate-release levodopa/benserazide 100/25 mg (Prolopa® 100-25)

Timeline

Start
2008-09
Primary completion
2008-11
Completion
2008-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Levodopa Small molecule 100 mg Oral
Subject Opicapone Small molecule 25 mg Oral
Subject Opicapone Small molecule 50 mg Oral
Subject Opicapone Small molecule 100 mg Oral
Background benserazide Small molecule 25 mg Oral

Indications

Parkinson disease