Bioavailability of Dabigatran and Amiodarone After Multiple Oral Administrations of Dabigatran Etexilate With or Without Amiodarone as Single Dose in Healthy Male and Female Volunteers

Phase 1 Completed 24 enrolled Boehringer Ingelheim

RandomizedParallel-groupOpen-labelTreatment

Summary

Investigation of the bioavailability, safety and tolerability of dabigatran with and without concomitant administration of amiodarone and the bioavailability of amiodarone and desethylamiodarone after administration of a single dose of amiodarone with and without dabigatran

Timeline

Start: 2006-04
Primary completion: 2006-06
Completion: —

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Amiodarone	Small molecule	600 mg	Oral
Subject	Dabigatran etexilate	Unknown	150 mg	Oral

Indications

No indication recorded.