drugset / Trial / NCT02174211
A Pharmacokinetic Study: Ranibizumab, Aflibercept and the Effect of Vitrectomy.
Non-randomizedParallel-groupOpen-labelTreatment
Summary
To study the effect of pars plana vitrectomy on the intravitreal pharmacokinetics of ranibizumab and to compare the half-life of ranibizumab and aflibercept.
Timeline
- Start
- 2014-06
- Primary completion
- 2020-11
- Completion
- 2020-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aflibercept | Protein / enzyme biologic | — | Intravitreal |
| Comparator | Ranibizumab | Monoclonal antibody | — | Intravitreal |