drugset / Trial / NCT02182167
A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis
Phase 2/3
Completed
102 enrolled
University of Cape Town
Medical Research Council, South Africa · collab
RandomizedSingle-groupQuadruple-blindTreatment
Summary
We will conduct a randomized placebo controlled trial to determine whether administration of intravenous (IV) NAC to participants with TB DIH, in dosages similar to that used in paracetamol poisoning, can improve recovery from hepatotoxicity.
Timeline
- Start
- 2014-05
- Primary completion
- 2019-02
- Completion
- 2019-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | N-acetylcysteine | Small molecule | 100 mg/kg | Intravenous |