drugset / Trial / NCT02184286

Pharmacokinetic Interaction Between Nevirapine and Saquinavir-sgc in HIV-1 Infected Patients

NCT02184286

Phase 1 Terminated 5 enrolled Boehringer Ingelheim
NaSingle-groupOpen-labelTreatment

Summary

The objectives of this study are to determine the effects of nevirapine on the steady-state pharmacokinetics of saquinavir-sgc and to determine the effects of saquinavir-sgc on the steady-state pharmacokinetics of nevirapine. This study will also evaluate the pharmacokinetics of nevirapine in combination with saquinavir-sgc compared to historical controls treated with nevirapine but without saquinavir-sgc.

Timeline

Start
1999-05
Primary completion
2000-02
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Nevirapine Small molecule 200 mg
Subject Saquinavir Small molecule 1600 mg