Drugs / Nevirapine
last change Dec 2024 re-read 2 minutes ago

Nevirapine

Small molecule

Developed for
HIV infectious disease · tuberculosis · AIDS · lipodystrophy · HIV wasting syndrome · hyperlipoproteinemia · Kaposi's sarcoma · central nervous system disorder
+2 more · dementia · hepatitis C virus infection
Investigated by
National Institute of Allergy and Infectious Diseases (NIAID) · Boehringer Ingelheim · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Bristol-Myers Squibb · Harvard School of Public Health (HSPH) · French National Agency for Research on AIDS and Viral Hepatitis
+85 more · National Institute of Mental Health (NIMH) · Glaxo Wellcome · International Maternal Pediatric Adolescent AIDS Clinical Trials Group · Makerere University · AIDS Care Research in Africa · ANRS, Emerging Infectious Diseases · Abbott · Bamrasnaradura Infectious Diseases Institute · Centers for Disease Control and Prevention · Fight AIDS and Infectious Diseases Foundation · Germans Trias i Pujol Hospital · Gilead Sciences · Merck Sharp & Dohme LLC · National AIDS Control Organisation · National Institute on Drug Abuse (NIDA) · Research Institute for Development · University of California, San Diego · AIDS Malignancy Consortium · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · All India Institute of Medical Sciences · Amsterdam UMC, location VUmc · Ann & Robert H Lurie Children's Hospital of Chicago · Botswana Harvard Health Partnership · Botswana Ministry of Health · Brigham and Women's Hospital · CIHR Canadian HIV Trials Network · Chulalongkorn University · Cipla Medpro · Columbia University · Department of Foreign Affairs, Ireland · Dermatological Society of South Africa · Doris Duke Charitable Foundation · Guangdong Provincial Maternal and Child Health Hospital · HIV Prevention Trials Network · Health Research Board, Ireland · Hospital San Jaime de Calella · Hospital de Calella · Indian Council of Medical Research · Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba · International Antiviral Therapy Evaluation Center · Johns Hopkins Bloomberg School of Public Health · Kirby Institute · Liverpool School of Tropical Medicine · MEDEX · Mahidol University · Maternal and Child Health Hospital of Guangxi Province · Maternal and Child Health Hospital of Sichuan Province · Maternal and Child Health Hospital of Xinjiang Uygur Autonomous Region · Maternal and Child Health Hospital of Yunan Province · McGill University Health Centre/Research Institute of the McGill University Health Centre · Medecins Sans Frontieres, Netherlands · Ministry of Science and Technology of the People´s Republic of China · National Cancer Institute (NCI) · National Center for AIDS/STD Control and Prevention, China CDC · National Center for Women and Children's Health, China CDC · National Heart, Lung, and Blood Institute (NHLBI) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · National Institutes of Health (NIH) · National Research Foundation, Singapore · PENTA Foundation · Parexel · Peking Union Medical College · Princess Marina Hospital, Botswana · Ragon Institute of MGH, MIT and Harvard · Ratiopharm GmbH · Roxane Laboratories · St Vincent's Hospital, Sydney · Stanford University · Tibotec BVBA · Triangle Pharmaceuticals · Tuberculosis Research Centre, India · University Hospital, Caen · University of British Columbia · University of Cape Town · all 91 on the full record

Regulatory milestones approvals, filings & regulatory actions · 8 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (2) US (FDA) VIRAMUNE XR 2012-09-28 – 2012-11-08 fda.gov
Label expansions (4) US (FDA) VIRAMUNE 1998-05-20 – 2008-06-24 fda.gov
Approved EU (EMA) Viramune 1998-02-04 europa.eu
Approved US (FDA) VIRAMUNE 1996-06-21 fda.gov

Trials 126 · started per year

today
US approved 1996
EU approved 1998
2
2
1
1
6
6
3
11
10
10
11
11
9
10
6
5
1
1
2
2
2
1
1
1994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 125 trials
Phase 1 NCT02202005 Aug 2014 → Jul 2015 Ratiopharm GmbH Completed No outcome recorded
Phase 1 NCT02194218 Sep → Nov 2009 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT00905489 Jun 2009 → Sep 2012 HIV infectious disease Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT00910806 Jun 2009 → Jun 2010 HIV infectious disease Tibotec BVBA Completed No outcome recorded
Phase 1 NCT02184312 Apr → Jul 2008 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02194179 Dec 2006 → May 2007 HIV infectious disease Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02192463 Apr → Aug 2006 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02191189 May 2005 → Jan 2006 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT00307502 Jan 2005 → Dec 2009 HIV infectious disease Germans Trias i Pujol Hospital Completed No outcome recorded
Phase 1 NCT00730223 Mar 2004 → Mar 2006 HIV infectious disease Vanderbilt University Completed No outcome recorded
Phase 1/24 trials
Phase 1/2 NCT02140255 Jan 2015 → Jan 2028 expected HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Recruiting No outcome recorded
Phase 1/2 NCT00672412 Oct 2008 → Jan 2010 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1/2 NCT00312091 Dec 2006 → Sep 2008 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1/2 NCT00260078 Feb 2006 → Apr 2009 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 220 trials
Phase 2 NCT02116660 Sep 2014 → Jul 2017 HIV infectious disease Merck Sharp & Dohme LLC Terminated No outcome recorded
Phase 2 NCT00640887 Feb 2009 → Oct 2010 HIV infectious disease, tuberculosis French National Agency for Research on AIDS and Viral Hepatitis Completed No outcome recorded
Phase 2 NCT00270296 Jun 2006 → Mar 2009 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00109590 Jun 2006 → Oct 2008 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00307151 Dec 2005 → Dec 2010 HIV infectious disease International Maternal Pediatric Adolescent AIDS Clinical Trials Group Completed No outcome recorded
Phase 2 NCT00146380 Jul 2003 → Jan 2009 HIV infectious disease Centers for Disease Control and Prevention Completed No outcome recorded
Phase 2 NCT00273975 Jan 2002 → Dec 2004 HIV infectious disease Boehringer Ingelheim Completed No outcome recorded
Phase 2 NCT00001688 Jan 1998 → Nov 2001 HIV infectious disease National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00001045 ? → Oct 1998 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00001083 ? → Jun 2001 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2/34 trials
Phase 2/3 NCT02369406 May 2015 → Nov 2020 overdue AIDS Harvard School of Public Health (HSPH) Active not recruiting No outcome recorded
Phase 2/3 NCT00495326 Dec 2007 → Apr 2011 AIDS, tuberculosis French National Agency for Research on AIDS and Viral Hepatitis Completed No outcome recorded
Phase 2/3 NCT00624195 Mar 2007 → Feb 2012 HIV infectious disease University of California, San Diego Completed No outcome recorded
Phase 2/3 NCT00039741 Aug 2002 → Aug 2009 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 332 trials
Phase 3 NCT01511237 Dec 2011 → Jun 2015 HIV infectious disease Research Institute for Development Completed No outcome recorded
Phase 3 NCT00819052 Dec 2008 → Jan 2012 HIV infectious disease Boehringer Ingelheim Completed No outcome recorded
Phase 3 NCT00573001 Jul 2008 → Jul 2011 HIV infectious disease French National Agency for Research on AIDS and Viral Hepatitis Completed No outcome recorded
Phase 3 NCT00561925 Nov 2007 → Nov 2011 HIV infectious disease Boehringer Ingelheim Completed No outcome recorded
Phase 3 NCT00427297 Sep 2007 → May 2009 HIV infectious disease University of Washington Terminated No outcome recorded
Phase 3 NCT01805258 Jun 2007 → Dec 2012 tuberculosis All India Institute of Medical Sciences Completed No outcome recorded
Phase 3 NCT00483054 Jan 2007 → Dec 2008 HIV infectious disease, tuberculosis Bamrasnaradura Infectious Diseases Institute Completed No outcome recorded
Phase 3 NCT00074412 Jan 2007 → Sep 2011 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 3 NCT00089505 Nov 2006 → Aug 2010 HIV infectious disease Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections Completed No outcome recorded
Phase 3 NCT00332306 Jun 2006 → Jun 2009 HIV infectious disease, tuberculosis Tuberculosis Research Centre, India Unknown No outcome recorded
Phase 430 trials
Phase 4 NCT06337032 Aug 2024 → Mar 2034 expected HIV infectious disease Gilead Sciences Recruiting No outcome recorded
Phase 4 NCT03642704 Feb 2017 → Sep 2019 ANRS, Emerging Infectious Diseases Completed No outcome recorded
Phase 4 NCT03088410 Aug 2016 → Mar 2022 HIV infectious disease, diabetes mellitus Ann & Robert H Lurie Children's Hospital of Chicago Completed No outcome recorded
Phase 4 NCT02712801 Apr 2016 → Dec 2021 HIV infectious disease National Center for Women and Children's Health, China CDC Completed No outcome recorded
Phase 4 NCT01637558 Nov 2012 → Jul 2017 HIV infectious disease, tuberculosis University of Cape Town Completed No outcome recorded
Phase 4 NCT00753324 May 2009 → Jan 2012 HIV infectious disease University of North Carolina, Chapel Hill Completed No outcome recorded
Phase 4 NCT00617643 May 2008 → Jun 2009 HIV infectious disease, tuberculosis Makerere University Completed No outcome recorded
Phase 4 NCT00620438 Feb 2008 → Jul 2011 HIV infectious disease, tuberculosis Makerere University Unknown No outcome recorded
Phase 4 NCT00523458 Jul 2007 → Mar 2008 HIV infectious disease, tuberculosis Stanford University Terminated No outcome recorded
Phase 4 NCT00355719 Jan 2007 → Feb 2008 HIV infectious disease Germans Trias i Pujol Hospital Completed No outcome recorded
Phase not applicable11 trials
NCT00830856 Oct 2006 → Oct 2008 Cryptococcal meningitis, HIV infectious disease University of Zimbabwe Completed No outcome recorded
NCT00028314 Mar 2002 → Mar 2005 HIV wasting syndrome, lipodystrophy National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
NCT00016601 Jun 2001 → May 2004 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
NCT00000922 ? → Jan 2003 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
NCT00000634 ? → Jun 1995 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
NCT00000896 ? → Oct 2000 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
NCT00000895 ? → Aug 2001 HIV infectious disease, Mycobacterium avium complex disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
NCT00002407 HIV infectious disease Weill Medical College of Cornell University Completed No outcome recorded
NCT00002323 HIV infectious disease Boehringer Ingelheim Completed No outcome recorded
NCT00001111 ? → Jun 1995 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Also used as a comparator or background therapy in 47 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT00719602 Comparator Aug 2009 → Aug 2013 HIV infectious disease, malaria International Maternal Pediatric Adolescent AIDS Clinical Trials Group Completed No outcome recorded
Phase 13 trials
Phase 1 NCT00162149 Comparator Oct 2005 → Jul 2006 HIV infectious disease Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT00032669 Background Mar 2002 → Apr 2006 HIV infectious disease National Cancer Institute (NCI) Completed No outcome recorded
Phase 1 NCT00004580 Background HIV infectious disease Abbott Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01632891 Background Jan 2014 → Jun 2016 HIV infectious disease, parasitemia Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections Completed No outcome recorded
Phase 26 trials
Phase 2 NCT01789879 Comparator Mar → Sep 2014 HIV infectious disease University of Nebraska Completed No outcome recorded
Phase 2 NCT01174914 Comparator Mar 2008 → Mar 2010 The Ojai Foundation Completed No outcome recorded
Phase 2 NCT00099632 Background Mar 2006 → Apr 2010 HIV infectious disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00294892 Comparator Feb 2006 → Sep 2009 HIV infectious disease Radboud University Medical Center Completed No outcome recorded
Phase 2 NCT00476853 Comparator Oct 2005 → Sep 2008 HIV infectious disease, tuberculosis The HIV Netherlands Australia Thailand Research Collaboration Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT02285114 Background Jan 2015 → Nov 2019 Gilead Sciences Completed No outcome recorded
Phase 316 trials
Phase 3 NCT03631732 Comparator Aug 2018 → Aug 2019 HIV infectious disease Gilead Sciences Completed No outcome recorded
Phase 3 NCT02616783 Comparator Dec 2015 → Feb 2018 HIV infectious disease Gilead Sciences Completed No outcome recorded
Phase 3 NCT02605954 Comparator Nov 2015 → Jun 2017 HIV infectious disease Gilead Sciences Completed No outcome recorded
Phase 3 NCT02469246 Background Jun 2015 → Dec 2017 HIV infectious disease Gilead Sciences Completed No outcome recorded
Phase 3 NCT02397096 Background Jun 2015 → Feb 2018 HIV infectious disease Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 412 trials
Phase 4 NCT07014189 Comparator Apr 2019 → Jan 2023 HIV infectious disease Cantonal Hospital of St. Gallen Completed No outcome recorded
Phase 4 NCT02431975 Background Aug 2015 → Apr 2020 HIV infectious disease Columbia University Completed No outcome recorded
Phase 4 NCT01694017 Comparator Nov 2012 → Aug 2014 HIV infectious disease Tufts University Completed No outcome recorded
Phase 4 NCT01192035 Comparator May 2011 → Sep 2014 University of Aarhus Completed No outcome recorded
Phase 4 NCT01340950 Comparator Jul 2010 → Jul 2014 HIV infectious disease, central nervous system disorder, dementia University of California, San Diego Completed No outcome recorded
Phase not applicable7 trials
NCT03664440 Comparator Dec 2016 → Oct 2017 Mahidol University Completed No outcome recorded
NCT02002286 Background Aug 2011 → May 2013 HIV infectious disease LI Taisheng Completed No outcome recorded
NCT01277627 Comparator Jan 2011 → Jul 2012 hepatitis C virus infection Valme University Hospital Unknown No outcome recorded
NCT00428116 Comparator Sep 2007 → Jul 2013 HIV infectious disease University of Washington Terminated No outcome recorded
NCT00255840 Comparator Jul 2006 → Jan 2009 HIV infectious disease CIPRA SA Completed No outcome recorded

Evidence & citations 20 cited values

Every value below carries the sentence it was read from. 185 sources stand behind the page.

FieldValueCited text
Known as Nevirapine “Generic names: Efavirenz/Emtricitabine/Tenofovir, Lamivudine/Zidovudine, Emtricitabine, Lamivudine, Abacavir/Lamivudine, Zidovudine, Abacavir/Lamivudine/Zidovudine,...” NCT00624195
172

“It may include one or two nucleoside reverse transcriptase inhibitors, such as zidovudine, didanosine, lamuvidine, zalcitabine, stavudine), a non- nucleoside reverse...” NCT00032669

“The study-treatment were lopinavir/r 100/400mg bid or indinavir/r 100/400mg bid for PI-class, for NNRTI-class, efavirenz or nevirapine and all NRTIs except D4T and DDC at usual dosage.” NCT00122668

“Participants who will be enrolled in this trial would keep their previous combined antiretroviral therapy, such as zidovudine or stavudine plus lamivudine plus nevirapine or efavirenz.” NCT02002286

“Triomune® (Cipla, Mumbai) Stavudine 40mg b.d \> 60 kg , 30mg bd \<60kg Lamivudine 150mg b.d \> 50 kg 2mg/kg \< 50 kg Nevirapine 200mg b.d ( 200mg daily for first 2 weeks)” NCT00380770

“Tenofovir+Emtricitabine+Third agent (Including a non nucleoside reverse transcriptase inhibitor: efavirenz or nevirapine or etravirine or rilpivirine” NCT02302547

“Baseline regimen of antiretroviral therapy with a NNRTI (efavirenz, nevirapine, or rilpivirine) administered according to the product circular” NCT02397096

nevirapine: 15mg/OD if weight ≥ 2500g / 10mg/OD if weight = 2000-2499g / 2mg/kg/OD if weight \< 2000g for 12 weeks in case of HIV-1 infection.” NCT03642704

“Bioavailability of 2 Different Nevirapine Extended Release Formulations Compared to Viramune® in HIV-1 Infected Subjects” NCT02194179

“efavirenz (EFV), rilpivirine (RPV), raltegravir (RAL), dolutegravir (DTG), maraviroc (MVC), or nevirapine (NVP)” NCT02469246

“Allowed unboosted 3rd ARV agents: efavirenz (EFV), raltegravir (RAL), dolutegravir (DTG), or nevirapine (NVP)” NCT02285114

“The NNRTI (nevirapine or efavirenz) was chosen by clinicians according to local availability and age.” NCT02028676

“women received antenatal zidovudine and peripartum nevirapine, the standard of care at the time.” PMID 23324656 May 2013

“zidovudine 300 mg + lamivudine 150 mg + nevirapine 200 mg , once daily, for a year” NCT01694017

“Treatment with nevirapine (400mg retard) and lamivudine (300mg) once daily” NCT07014189

“allowed NNRTIs include efavirenz (EFV), nevirapine, or rilpivirine.” NCT01495702

“Accepted NNRTIs: efavirenz (EFV), nevirapine (NVP)” NCT00039741

“plus nevirapine (NVP) 200 mg orally twice daily” NCT01435018

“AZT/3TC/NVP (zidovudine/lamivudine/nevirapine)” NCT00428116

“Azidothimidine + lamivudine + nevirapine Or” NCT01174914

Nevirapine immediate release (IR) 200 mg” NCT02192463

nevirapine (NVP; Viramune®)” NCT02605954

nevirapine (NVP;Viramune®)” NCT02616783

“unboosted nevirapine (NVP)” NCT06337032

nevirapine (NVP;Viramune®)” NCT02121795

nevirapine (NVP)” NCT03631732

NCT01192035

NCT00004580

NCT00001083

NCT02116660

NCT00552240

NCT00001091

NCT00001095

NCT00001108

NCT00001111

NCT00006396

NCT00483054

NCT00000781

NCT00167674

NCT00730223

NCT00409591

NCT00001135

NCT02431975

NCT00312091

NCT00620438

NCT00102960

NCT00000872

NCT00573001

NCT00355719

NCT00000869

NCT02182765

NCT00004855

NCT00099632

NCT00021671

NCT02181933

NCT02202005

NCT00122226

NCT00000902

NCT00164736

NCT00117728

NCT00000634

NCT00427297

NCT02181946

NCT00476853

NCT02182791

NCT00016601

NCT00001045

NCT01061151

NCT03664440

NCT00260078

NCT00099359

NCT02140255

NCT00006279

NCT00061321

NCT00089505

NCT00415090

NCT00074399

NCT00978068

NCT00910806

NCT01789879

NCT00703898

NCT02369406

NCT01511237

NCT02184091

NCT00001688

NCT00074412

NCT00307502

NCT00087464

NCT00704249

NCT01340950

NCT02712801

NCT00389207

NCT00540137

NCT00028314

NCT00001644

NCT00197587

NCT00013520

NCT00618176

NCT00661349

NCT01632891

NCT00294892

NCT00274001

NCT01277627

NCT00004581

NCT00021463

NCT00017719

NCT00307151

NCT00000922

NCT00197613

NCT00000924

NCT00146380

NCT00002418

NCT00143689

NCT00455585

NCT00002407

NCT00617643

NCT00640887

NCT00109590

NCT00000747

NCT00523458

NCT00639938

NCT00002381

NCT01772940

NCT00332306

NCT00002194

NCT00002368

NCT00719602

NCT00398684

NCT00000895

NCT00144157

NCT00000896

NCT03088410

NCT00000649

NCT00234091

NCT00335686

NCT00002347

NCT02184286

NCT00115648

NCT00002324

NCT00002323

NCT00000962

NCT02184078

NCT00000770

NCT00074581

NCT00495326

NCT00819052

NCT00199979

NCT00127972

NCT00000814

NCT00830856

NCT00905489

NCT00405171

NCT00273975

NCT00162149

NCT01637558

NCT00273988

NCT00192660

NCT00255840

NCT00561925

NCT02184312

NCT01805258

NCT00672412

NCT00344461

NCT02194218

NCT00000808

NCT00144261

NCT00144248

NCT02184299

NCT00002166

NCT00000942

NCT02191189

NCT00270296

NCT00144183

Known as BI-RG-587 “An Open-Label, Pilot Study to Evaluate the Development of Resistance to Nevirapine (BI-RG-587) in HIV-Infected Patients With CD4 Cell Count >= 500/mm3” NCT00000747
3

“Nevirapine (BI-RG-587) has shown in vitro inhibitory activity against HIV-1 reverse transcriptase (RT).” NCT00000962

“Nevirapine (BI-RG-587) has shown in vitro inhibitory activity against HIV-1 reverse transcriptase” NCT00001111

“nevirapine (BI-RG-587) plasma levels” NCT00000634

Known as BIRG 0587 ChEMBL registry synonym — accepted as the source's own label CHEMBL57
Known as Neviparine Neviparine (NVP)/ Lamivudine (3TC)” NCT07014189
Known as Nevirapina ChEMBL registry synonym — accepted as the source's own label CHEMBL57
Known as Nevirapine anhydrous ChEMBL registry synonym — accepted as the source's own label CHEMBL57
Known as Nevirapine teva ChEMBL registry synonym — accepted as the source's own label CHEMBL57
Known as Nevirapinum anhydrous ChEMBL registry synonym — accepted as the source's own label CHEMBL57
Known as NSC-641530 ChEMBL registry synonym — accepted as the source's own label CHEMBL57
Known as NVP “The objective was to establish the pharmacokinetic (PK) profile at steady state of two different nevirapine (NVP) extended release (XR) formulations at 300 mg or 400 mg daily...” NCT02194179
57

“In Pediatric AIDS Clinical Trials Group 377, antiretroviral therapy-experienced children were randomized to 4 treatment arms that included different combinations of stavudine,...” PMID 11372025 May 2001

“The efficacy and tolerance of switching from zidovudine (ZDV) and lamivudine (3TC) in clinically stable HIV-infected children with incomplete viral suppression to stavudine...” PMID 11840078 Feb 2002

“Patients in Arm B-1 will discontinue their current HAART and will receive a PI and a nonnucleoside reverse transcriptase inhibitor (NNRTI), either lopinavir/ritonavir (LPV/r)...” NCT00028314

“The purpose of this study is to see if nevirapine (NVP) or zidovudine (AZT), given to mothers during labor and delivery and to their babies during the first week of life, can...” NCT00006396

“An open-label phase 1/2 study was designed to assess the safety and trough concentrations of nevirapine (NVP) given once weekly (OW), twice weekly (TW), or once daily (OD) to...” PMID 14657758 Dec 2003

“Treatment-naive adults were randomized to nevirapine (NVP) or ritonavir-boosted lopinavir (LPV/r) regimens each in combination with tenofovir (TDF)/emtricitabine (FTC) or...” PMID 25028911 May 2014

“The Effect of Single Dose Carbamazepine on the Pharmacokinetics of Single Dose Nevirapine (Viramune, NVP) and Development of NVP Resistance, PMTCT Program of Moshi, Tanzania (VITA1)” NCT00294892

“Nevirapine (NVP) can be safely and effectively administered once-daily but has not been assessed in human immunodeficiency virus (HIV)-infected patients with tuberculosis (TB).” PMID 21890776 Oct 2011

“The 7 drugs that will be given in this study are stavudine (d4T), didanosine (ddI), lamivudine (3TC), nelfinavir (NFV), ritonavir (RTV), saquinavir (SQV), and nevirapine (NVP).” NCT00001108

“Nevirapine (NVP) resistance emerges in up to 70% of women exposed to single-dose (sd) NVP for prevention of mother-to-child transmission of human immunodeficiency virus (HIV).” PMID 23300238 Jan 2013

“receive individualized regimen of HAART for 48 weeks: nelfinavir (NEV), nevirapine (NVP), and nucleoside reverse transcriptase inhibitor(s) as per primary physician.” NCT00000895

“300 mg of zidovudine (ZDV), 150 mg of lamivudine, and 200 mg nevirapine (NVP) was given twice daily from 34 weeks gestation until six months after delivery.” NCT00167674

“BACKGROUND: We aim here to determine the appropriate dose of nevirapine (NVP) in Thai HIV-tuberculosis (TB)-coinfected patients receiving rifampicin.” PMID 18672531 2008

“The relationship between the CYP2B6-G516T genotype and nevirapine (NVP) pharmacokinetics in plasma and cerebrospinal fluid (CSF) is limited.” PMID 18090046 Oct 2007

“In the nevirapine/lopinavir/ritonavir (NVP/LPV/r) group, hepatic insulin sensitivity had improved compared with baseline after 24 months.” PMID 19898246 Feb 2010

“The Fixed Drug Combination (FDC) nevirapine (NVP)-lamivudine-stavudine is the first line ART available for low-income countries.” NCT00495326

“To assess the effectiveness of the addition of a single dose of nevirapine (NVP) to Zidovudine (ZDV, also known as AZT)” NCT00197587

“efavirenz (EFV), rilpivirine (RPV), raltegravir (RAL), dolutegravir (DTG), maraviroc (MVC), or nevirapine (NVP)” NCT02469246

“after receiving nevirapine (NVP) 200 mg quaue die (QD) for 2 weeks, pt titrated to NVP 200 mg bis in die (BID)” NCT00552240

“Allowed unboosted 3rd ARV agents: efavirenz (EFV), raltegravir (RAL), dolutegravir (DTG), or nevirapine (NVP)” NCT02285114

“The drug combination will contain didanosine (ddI) plus stavudine (d4T) plus nevirapine (NVP) plus MKC-442.” NCT00002418

“All HIV-infected women and their neonates will be offered the HIVNET 012 nevirapine (NVP) regimen.” NCT00021671

“NFV 50-55 mg/kg bid, nevirapine (NVP) 120 mg/m bid and stavudine (d4T) 1 mg/kg bid (arm B)” PMID 16220085 Oct 2005

“giving the anti-HIV drug nevirapine (NVP) to HIV-positive pregnant women and their infants” NCT00001135

“giving the anti-HIV drug nevirapine (NVP) to HIV-positive pregnant women and their babies” NCT00000942

“single dose of the drug nevirapine (NVP) given to pregnant women at onset of labor” NCT00398684

“200 mg nevirapine (NVP) administered as 4 x 50 mg extended release (XR) tablets” NCT02194218

“The study-specified NNRTIs will be nevirapine (NVP) or efavirenz (EFV).” NCT00000922

“Nevirapine (NVP) Use to Prevent Mother-to-Child Transmission of HIV” NCT00074399

“single-dose nevirapine (NVP) + 1-week zidovudine (ZDV) (control)” PMID 21423025 Aug 2011

“single dose of nevirapine (NVP) for women during labor” NCT00061321

“Accepted NNRTIs: efavirenz (EFV), nevirapine (NVP)” NCT00039741

“didanosine (ddI) plus AZT plus nevirapine (NVP);” NCT00000814

“indinavir (IDV), nevirapine (NVP), 3TC, and d4T” NCT00001095

“plus nevirapine (NVP) 200 mg orally twice daily” NCT01435018

“AZT/3TC/NVP (zidovudine/lamivudine/nevirapine)” NCT00427297

“AZT/3TC/NVP (zidovudine/lamivudine/nevirapine)” NCT00428116

“Nevirapine (NVP) is approved for BID dosing.” NCT00344461

“steady-state nevirapine (NVP) 200 mg b.i.d.” NCT00910806

“Nevirapine (NVP): Antepartum Mothers” NCT01061151

“nevirapine (NVP) 200 mg twice daily” NCT00389207

“Neviparine (NVP)/ Lamivudine (3TC)” NCT07014189

“nevirapine (NVP) -based regimen” NCT00117728

“Nevirapine (NVP) 200 mg tablets” NCT02116660

“nevirapine (NVP; Viramune®)” NCT02605954

“unboosted nevirapine (NVP)” NCT06337032

“Nevirapine (NVP) treatment” NCT00661349

“Nevirapine (NVP) 200mg bid” NCT00618176

“nevirapine (NVP;Viramune®)” NCT02616783

“Drug: Nevirapine (NVP)” NCT00099359

“Nevirapine (NVP)” NCT00144183

“nevirapine (NVP)” NCT03631732

“nevirapine (NVP)” NCT00000896

“nevirapine (NVP)” NCT00004581

“Nevirapine (NVP)” NCT00978068

“Nevirapine (NVP)” NCT02140255

“nevirapine (NVP)” NCT00312091

Known as NVP IR “The primary objective of this study is to evaluate the efficacy of 400 mg QD nevirapine extended release (NVP XR) formulation versus 200 mg BID nevirapine immediate release...” NCT00561925
Known as NVP XR “The primary objective of this study is to evaluate the efficacy of 400 mg QD nevirapine extended release (NVP XR) formulation versus 200 mg BID nevirapine immediate release...” NCT00561925
Known as NVP: nevirapine, Viramune NVP: nevirapine, ViramuneNCT02028676
Known as Viramune “An International, Double Blind, Randomized, Phase III Study to Evaluate the Tolerance, Safety, and Effectiveness of Viramune (Nevirapine) in Preventing Clinical AIDS...” NCT00002368
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“An Investigation of the Potential Pharmacokinetic Interaction Between Nevirapine (Viramune) and Nelfinavir (Viracept) and the Efficacy of This Combination Therapy in HIV-1...” NCT00002381

“The purpose of this trial is to compare the effect of switching to nevirapine (Viramune®)-containing regimen on quality of life of patients with fat abnormalities and...” NCT00274001

“The Effect of Single Dose Carbamazepine on the Pharmacokinetics of Single Dose Nevirapine (Viramune, NVP) and Development of NVP Resistance, PMTCT Program of Moshi, Tanzania (VITA1)” NCT00294892

“A Pharmacokinetic Study to Evaluate the Interaction Between Nevirapine (Viramune®) and Methadone in HIV-1 Infected, Opioid-dependent Adults on Stable Methadone Maintenance Therapy” NCT00273988

“An Open-Label, Non-Randomized Trial to Evaluate the Tolerability and Safety of Viramune (Nevirapine) in Adult and Pediatric Patients With Progressive HIV Disease” NCT00002166

“An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.” NCT00002194

“Study to Determine the Effects of Nevirapine (VIRAMUNE®) on the Steady State Pharmacokinetics of Rifabutin (MYCOBUTIN®) in HIV+ Patients” NCT02184078

“lopinavir/ritonavir (Kaletra) and nevirapine (Viramune) twice a day;” NCT00143689

“Nevirapine (Viramune): tablets 200 mg (1 tablet/12h\*)” NCT00355719

“Nevirapine (Viramune): 1 comp (200mg)/12h” NCT00335686

“nevirapine (Viramune) dosing regimens” NCT00389207

“nevirapine (NVP; Viramune®)” NCT02605954

“nevirapine (NVP;Viramune®)” NCT02616783

“NVP IR 200 mg (Viramune®)” NCT02194179

“Nevirapine (VIRAMUNE®)” NCT02184286

“Nevirapine (VIRAMUNE®)” NCT02184299

“Nevirapine (VIRAMUNE®)” NCT02184312

“Nevirapine (VIRAMUNE)” NCT02182791

Known as Viramune (nevirapine) Viramune (nevirapine)NCT00523458
Known as Viramune (Nevirapine) suspension 50mg/5ml Viramune (Nevirapine) suspension 50mg/5mlNCT00164736
Known as Viramune xr ChEMBL registry synonym — accepted as the source's own label CHEMBL57
Action Inhibit “Test tube studies have shown that nevirapine (BI-RG-587) inhibits replication (reproduction) of HIV.” NCT00000634
Modality Small molecule “non-nucleoside reverse transcriptase inhibitor” NCT00000781
Route Oral “Two doses, given by mouth, are evaluated” NCT00000634