drugset / Trial / NCT00273975

Trial to Evaluate Steady State Pharmacokinetic Parameters, Efficacy and Safety of Nevirapine in Antiretroviral Drug naïve Pediatric Patients

NCT00273975

Phase 2 Completed 123 enrolled Boehringer Ingelheim
RandomizedParallel-groupOpen-labelTreatment

Summary

Trial to evaluate steady state pharmacokinetic parameters of nevirapine 150mg/m2 and nevirapine 4 or 7 mg/kg after 4 weeks, and efficacy and safety of the dosing when administered for 48 weeks in antiretroviral drug naïve paediatric patients.

Timeline

Start
2002-01
Primary completion
2004-12
Completion
2004-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Nevirapine Small molecule 4 mg/kg
Subject Nevirapine Small molecule 7 mg/kg
Subject Nevirapine Small molecule 150 mg/m2
Background Lamivudine Other / unclassified
Background Zidovudine Small molecule