drugset / Trial / NCT00021463

Changing to Nonprotease Inhibitor Treatment to Improve Side Effects

NCT00021463 ↗

Treatment

Summary

The purpose of this study is to learn whether changing from a type of anti-HIV drug called a protease inhibitor (PI) to another type of anti-HIV drug will help to lower the amount of fats or sugars in the blood. PIs have been effective at keeping HIV viral load (amount of HIV in the blood) down. However, some people who take PIs have higher than normal levels of fats and/or sugars in the blood. Doctors believe that switching to anti-HIV drugs that do not contain PIs will improve the abnormal side effects. This study will test 3 different combinations of non-PI drugs to see which may improve side effects while keeping viral loads low.

Timeline

Start
—
Primary completion
2002-02
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Abacavir Other / unclassified — —
Subject Efavirenz Other / unclassified — —
Subject Lamivudine Other / unclassified — —
Subject Nevirapine Small molecule — —
Subject Zidovudine Small molecule — —