drugset / Trial / NCT01694017
Economic, Clinical and Quality of Life Assessment in Patients on Antiretroviral Therapy
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare clinical, economical and quality of life (QOL) outcomes in patients living with HIV on zidovudine/stavudine regimen and tenofovir regimen. This study will be an unblinded randomized trial. The first step will be empirical data collection for one year for calculating the incremental cost effectiveness ratio (ICER). The second step will be to perform a simulation model for calculating long term ICER.
Timeline
- Start
- 2012-11
- Primary completion
- 2014-08
- Completion
- 2014-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Efavirenz | Other / unclassified | 600 mg | — |
| Comparator | Lamivudine | Other / unclassified | 150 mg | — |
| Comparator | Nevirapine | Small molecule | 200 mg | — |
| Comparator | Tenofovir | Small molecule | 300 mg | — |
| Comparator | Zidovudine | Small molecule | 300 mg | — |
| Comparator | emtricitabine | Other / unclassified | 200 mg | — |