drugset / Trial / NCT02186821

Ceritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1 (SIGNATURE)

NCT02186821

Phase 2 Terminated 47 enrolled Novartis Pharmaceuticals
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this signal seeking study was to determine whether treatment with ceritinib demonstrated sufficient efficacy in select pathway-activated solid tumors and/or hematologic malignancies to warrant further study.

Timeline

Start
2014-09-17
Primary completion
2017-12-13
Completion
2017-12-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Ceritinib Small molecule 750 mg Oral

Indications

No indication recorded.