drugset / Trial / NCT02193815
A 12 Day Study To Evaluate A Topical Drug To Treat Plaque Psoriasis
RandomizedParallel-groupDouble-blindTreatment
Summary
This is a vehicle and comparator controlled Proof of Mechanism (PoM) trial to evaluate the effect on psoriasis disease activity and safety of topically applied PF 06263276 in subjects with psoriasis vulgaris.
Timeline
- Start
- 2014-09
- Primary completion
- 2015-02
- Completion
- 2015-02
Outcome
Missed primary endpoint
registry PF-06263276 4% Solution vs PF-06263276 Vehicle; p = 0.3465 NCT02193815 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Calcipotriol | Small molecule | 0.01 mg | Topical |
| Subject | PF06263276 | Small molecule | 8 mg | Topical |
| Subject | Tofacitinib | Small molecule | 4 mg | Topical |