drugset / Trial / NCT02195973

Phase IB Trial of LDE225 and Paclitaxel in Recurrent Ovarian Cancer

NCT02195973

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to find out if a new drug, LDE225, is safe and has beneficial effects when combined with paclitaxel in women with platinum resistant ovarian cancer. Platinum resistant ovarian cancer refers to recurrent ovarian cancer that has undergone chemotherapy inclusive of a platinum compound (e.g. carboplatin or cisplatin).

Timeline

Start
2014-09
Primary completion
2016-12-10
Completion
2017-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Paclitaxel Small molecule Intravenous
Subject Sonidegib Small molecule Oral

Indications