Safety and Pharmacokinetics Study of Redosing EXPAREL in Healthy Volunteers

Phase 1 Completed 60 enrolled Pacira Pharmaceuticals, Inc

Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and pharmacokinetics of redosing EXPAREL via local subcutaneous infiltration in healthy volunteers.

Timeline

Start: 2014-08
Primary completion: 2014-09
Completion: 2014-09

Publications

Rice D, Heil JW, Biernat L. Pharmacokinetic Profile and Tolerability of Liposomal Bupivacaine Following a Repeated Dose via Local Subcutaneous Infiltration in Healthy Volunteers. Clin Drug Investig. 2017 Mar;37(3):249-257. doi: 10.1007/s40261-017-0495-2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Bupivacaine	Other / unclassified	266 mg	Subcutaneous

Indications

No indication recorded.