drugset / Trial / NCT02222441
Effect Of Modafinil And Pioglitazone On The Pharmacokinetics Of Palbociclib (PD-0332991)
Non-randomizedCrossoverOpen-labelBasic science
Summary
This study is designed to evaluate the potential effect of the moderate CYP3A inducer modafinil and the weak CYP3A inducer pioglitazone on the pharmacokinetics of palbociclib.
Timeline
- Start
- 2014-10
- Primary completion
- 2014-12
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Modafinil | Small molecule | 400 mg | — |
| Subject | Palbociclib | Small molecule | 125 mg | Oral |
| Subject | Pioglitazone | Small molecule | 45 mg | — |
Indications
No indication recorded.