drugset / Trial / NCT02224729

Bendamustine Hydrochloride, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma

NCT02224729 ↗

NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies side effects and how well bendamustine hydrochloride, bortezomib, and dexamethasone work in treating patients with newly diagnosed multiple myeloma. Drugs used in chemotherapy, such as bendamustine hydrochloride and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving bendamustine hydrochloride with bortezomib and dexamethasone may kill more cancer cells.

Timeline

Start
2014-08-25
Primary completion
2016-04-21
Completion
2018-11-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Bendamustine Small molecule — Intravenous
Subject Bortezomib Small molecule — Subcutaneous
Subject Dexamethasone Small molecule — Oral

Indications