drugset / Trial / NCT02226328
Nurse Administered Propofol Sedation vs. Midazolam With Fentanyl-sedation for Flexible Bronchoscopy: A Randomized, Single Blind, Controlled Study of Satisfaction and Safety.
RandomizedParallel-groupSingle-blindTreatment
Summary
Flexible bronchoscopy almost always requires sedation to be successful. In order to increase the availability of propofol for sedation, non-anaesthesiologist administered propofol sedation has been suggested as an alternative to traditional midazolam/opioid sedation or the general anaesthesia provided by anaesthesiologists. Hypothesis: Patients undergoing flexible bronchoscopy prefers non-anaesthesiologist administered sedation with propofol as opposed to non-anaesthesiologist administered sedation with midazolam and fentanyl. Propofol sedation is as safe as midazolam and fentanyl sedation.
Timeline
- Start
- 2014-11
- Primary completion
- 2015-12
- Completion
- 2016-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | 0.025 mg | — |
| Comparator | Fentanyl | Other / unclassified | 0.05 mg | — |
| Comparator | Midazolam | Small molecule | 1 mg | — |
| Subject | Propofol | Small molecule | 10 mg | — |
| Subject | Propofol | Small molecule | 20 mg | — |
Indications
No indication recorded.