drugset / Trial / NCT02228681
Everolimus and Letrozole or Hormonal Therapy to Treat Endometrial Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
The main purpose of this study is to evaluate the effectiveness of the combination of the drugs Everolimus and Letrozole compared to Tamoxifen and Medroxyprogesterone acetate in treating endometrial cancer and to determine the types and severity of side effects caused by treatment with these drug combinations.
Timeline
- Start
- 2015-05-21
- Primary completion
- 2018-01
- Completion
- 2024-08-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Everolimus | Small molecule | 10 mg | Oral |
| Subject | Letrozole | Other / unclassified | 2.5 mg | Oral |
| Comparator | Tamoxifen | Small molecule | 20 mg | Oral |
| Comparator | medroxyprogesterone acetate | Other / unclassified | 200 mg | Oral |