drugset / Trial / NCT02229266

Randomised Controlled Phase-2 Trial to Determine the Efficacy of Adoptive Immunotherapy With NK Cells in High-risk AML

NCT02229266 ↗

RandomizedParallel-groupOpen-labelTreatment

Summary

The trial investigates the efficacy of adoptive immunotherapy with haploidentical natural killer cells compared to standard chemotherapy (after first complete remission) in patients with a high-risk acute myeloid leukemia being older than 65 years of age and not eligible for allogeneic transplantation

Timeline

Start
2015-09
Primary completion
2017-04-22
Completion
2017-04-22

Outcome

Outcome not reported

Stopped (Enrollment): “low recruitment rate”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cytarabine Small molecule — —
Subject NK cells Cell therapy — Other