drugset / Trial / NCT02230033
Study to Assess Drug-Drug Interaction Between Itraconazole or Gemfibrozil and JNJ-56021927
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the effect of multiple doses of itraconazole or gemfibrozil on the pharmacokinetics (the study of the way a drug enters and leaves the blood and tissues over time) of JNJ-56021927 and its metabolites (JNJ 56142060 and JNJ-56142021) in healthy male participants.
Timeline
- Start
- 2014-09
- Primary completion
- 2014-12
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Apalutamide | Small molecule | 240 mg | Oral |
| Subject | Gemfibrozil | Small molecule | 600 mg | Oral |
| Subject | Itraconazole | Small molecule | 200 mg | Oral |
Indications
No indication recorded.