drugset / Trial / NCT02231710

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

NCT02231710

Phase 1 Terminated 1 enrolled Bellicum Pharmaceuticals
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine a safe dose of BPX-501 gene modified T cells infused after a haplo-identical stem cell transplant to facilitate engraftment and the safety of Rimiducid (AP1903) on day 7 to prevent GVHD.

Timeline

Start
2015-02
Primary completion
2015-09
Completion
2018-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Rimiducid Other / unclassified
Subject rivogenlecleucel Cell therapy 3e+06 cells/kg
Subject rivogenlecleucel Cell therapy 1e+07 cells/kg