drugset / Trial / NCT02233101

Oral vs. Intravenous TXA Study Proposal: TJA

NCT02233101

Completed 167 enrolled Rush University Medical Center
RandomizedParallel-groupOpen-labelPrevention

Summary

Purpose: Examine oral and intravenous Tranexamic Acid (TXA) to determine whether or not the different routes of drug administration are equivalent in terms of post-operative reduction in hemoglobin, number of transfusions, and post-operative blood loss following TJA surgery. Hypothesis: Oral and intravenous TXA are equivalent routes of drug administration.

Timeline

Start
2014-06
Primary completion
2015-08
Completion
2015-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tranexamic Acid Small molecule 1 g Oral
Comparator Tranexamic Acid Small molecule 1950 mg Oral

Indications

No indication recorded.