drugset / Trial / NCT02233452
Methadone and Ketamine for Neuropathic Pain Treatment
Phase 4
Completed
37 enrolled
Federal University of Santa Maria
Hospital de Clinicas de Porto Alegre · collabSanta Casa de Misericórdia de Belo Horizonte · collab
RandomizedFactorialQuadruple-blindTreatment
Summary
Methadone and ketamine are effective for neuropathic pain management. However, the benefits of the association of both drugs are uncertain. Here, the investigators conducted a randomized, double-blind, in parallel, active controlled clinical trial to test the hypothesis that methadone combined ketamine (methadone/ketamine) is more effective than methadone or ketamine alone in reducing neuropathic pain.
Timeline
- Start
- 2012-01
- Primary completion
- 2012-08
- Completion
- 2012-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketamine | Small molecule | — | Oral |
| Comparator | Methadone | Other / unclassified | — | Oral |