drugset / Trial / NCT02240927

Anticoagulation Regimens in Pregnant Patients With Prosthetic Heart Valves

NCT02240927

RandomizedParallel-groupOpen-labelTreatment

Summary

Pregnancy is associated with increased risk of thrombosis among women with mechanical prosthetic heart valves.However, the best anticoagulant treatment strategies for pregnant patients with prosthetic heart valves have been controversial. In this study the investigators wanted to identify the most effective and safe regimen among different anticoagulant regimens.

Timeline

Start
2010-01
Primary completion
2015-06
Completion
2015-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Enoxaparin sodium Other / unclassified 1 mg/kg
Comparator Warfarin Small molecule 2.5 mg
Comparator Warfarin Small molecule 4 mg