drugset / Trial / NCT02241083

The Effect of Norepinephrine and Dopamine on Radial Forearm Free Flap Tissue Oxygen Pressure and Microdialysate Metabolite Measurements

NCT02241083

Phase 4 Completed 25 enrolled Tampere University Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

Vasopressors may be needed after head and neck microvascular reconstructions to maintain sufficient mean arterial pressure. This is crucial for the flap survival. The study hypothesis is that norepinephrine and dopamine used as vasopressors do not affect flap tissue oxygen level and microdialysate metabolites.

Timeline

Start
2006-06
Primary completion
2014-05
Completion

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dopamine Small molecule
Comparator Norepinephrine Other / unclassified

Indications