drugset / Trial / NCT02248259
Drug Drug Interaction Trial With Strong CYP3A4 Inhibitor (Itraconazole) in CYP2C19 Extensive Metabolizers and Poor Metabolizers
RandomizedCrossoverOpen-labelTreatment
Summary
The objective of the current study is to evaluate the effect of once daily itraconazole on the pharmacokinetics of BI 409306 in poor (PM) and extensive metabolisers (EM) of CYP2C19.
Timeline
- Start
- 2014-10-08
- Primary completion
- 2015-01-07
- Completion
- 2015-01-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | 200 mg | Oral |
| Subject | OSORESNONTRINE | Small molecule | 25 mg | Oral |
Indications
No indication recorded.