drugset / Trial / NCT02251145
Effects of Tipranavir (TPV) and Ritonavir (RTV) on the Pharmacokinetic Characteristics of Tenofovir Disoproxil Fumarate in Healthy Volunteers
RandomizedParallel-groupOpen-labelTreatment
Summary
Study to characterise the effects of two dose combinations of tipranavir/ritonavir (TPV 500 mg/RTV 100 mg and TPV 750 mg/RTV 200 mg) administered BID, on the pharmacokinetics of tenofovir disoproxil fumarate as well as the effects of tenofovir disoproxil fumarate on the pharmacokinetics of tipranavir/ritonavir.
Timeline
- Start
- 2002-05
- Primary completion
- 2002-06
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ritonavir | Other / unclassified | 100 mg | — |
| Subject | Ritonavir | Other / unclassified | 200 mg | — |
| Subject | Tenofovir disoproxil fumarate | Small molecule | 300 mg | — |
| Subject | Tipranavir | Small molecule | 500 mg | — |
| Subject | Tipranavir | Small molecule | 750 mg | — |
Indications
No indication recorded.